| This Week’s Rank | Last Week’s Rank | Title | Street Date | Studio | Genre | Box Office (millions) | Blu-ray Share for Title | Index* | 3D%† | UHD%†† |
| 1 | 1 | Spider-Man: No Way Home | 4/12/22 | Sony Pictures/Marvel | Action | $804.58 | 68% | 100.00 | – | 19% |
| 2 | New | Jackass Forever | 4/19/22 | Paramount | Comedy | $57.74 | 59% | 12.56 | – | – |
| 3 | 2 | Sing 2 | 3/29/22 | Universal | Animated | $162.78 | 47% | 11.64 | – | 7% |
| 4 | 3 | Spider-Man 3-Movie Collection (MCU) | 4/12/22 | Sony Pictures/Marvel | Action | Re-release | 100% | 8.34 | – | – |
| 5 | 4 | Scream (2022) | 4/5/22 | Paramount | Horror | $81.64 | 43% | 6.59 | – | 8% |
| 6 | 9 | Yellowstone: Season 4 | 3/8/22 | Paramount | Western | Cable | 19% | 5.33 | – | – |
| 7 | New | Cyrano | 4/19/22 | Universal/MGM | Romance | $3.87 | 39% | 5.03 | – | – |
| 8 | 5 | Encanto | 2/8/22 | Disney | Animated | $96.09 | 37% | 5.00 | – | 6% |
| 9 | ** | The Cabin in the Woods | 9/18/12 | Lionsgate | Horror | Re-release | 99% | 4.15 | – | 99% |
| 10 | 6 | Sonic the Hedgehog | 5/19/20 | Paramount | Family | Re-release | 20% | 3.90 | – | 3% |
| 11 | 7 | Death on the Nile (2022) | 4/5/22 | 20th Century | Mystery | $45.63 | 48% | 3.71 | – | 12% |
| 12 | 11 | The Matrix Resurrections | 3/8/22 | Warner | Sci-Fi | $37.69 | 59% | 3.42 | – | 17% |
| 13 | New | Heavy Metal/Heavy Metal 2000 | 4/19/22 | Sony Pictures | Animated | Re-release | 100% | 3.41 | – | 100% |
| 14 | 12 | Venom: Let There Be Carnage | 12/14/21 | Sony Pictures | Action | $213.55 | 52% | 3.39 | – | 9% |
| 15 | 10 | Ghostbusters: Afterlife | 2/1/22 | Sony Pictures | Comedy | $129.36 | 54% | 3.33 | – | 14% |
| 16 | 18 | Fantastic Beasts 2-Film Collection | 9/25/19 | Warner | Fantasy | Re-release | 12% | 3.05 | – | – |
| 17 | 19 | Last Looks | 4/12/22 | RLJ | Comedy | DTV | 35% | 2.719 | – | – |
| 18 | 20 | Dune: Part One | 1/11/22 | Warner | Sci-Fi | $108.33 | 69% | 2.716 | 2% | 27% |
| 19 | 8 | Sing 2-Movie Pack | 3/29/22 | Universal | Animated | Re-release | 39% | 2.66 | – | – |
| 20 | 16 | Spider-Man: Far From Home | 10/1/19 | Sony Pictures/Marvel | Action | Re-release | 35% | 2.64 | – | 13% |
| Source: NPD VideoScan First Alert (based on unit sales from reporting retailers) | ||||||||||
| MediaPlayNews.com | ||||||||||
| * Units Sold Compared to No. 1 Title | ||||||||||
| ** Re-entered the Top 100 | ||||||||||
| † Percentage of Overall Disc Sales in a 3D format; 3D is considered a Blu-ray version and is also part of the BD Share for each title. | ||||||||||
| †† Percentage of Overall Disc Sales in a UHD BD format; UHD is considered a Blu-ray version and is also part of the BD Share for each title. | ||||||||||
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