| This Week’s Rank | Last Week’s Rank | Title | Street Date | Studio | Genre | Box Office (millions) | Blu-ray Share for Title | Index* | 3D%† | UHD%†† |
| 1 | 1 | The Suicide Squad | 10/26/21 | Warner | Action | $55.80 | 60% | 100.00 | – | 13% |
| 2 | New | Paw Patrol: The Movie | 11/2/21 | Paramount | Animated | $40.13 | 37% | 70.95 | – | – |
| 3 | 2 | Free Guy | 10/12/21 | Disney/20th Century | Comedy | $121.54 | 61% | 42.99 | – | 18% |
| 4 | 3 | Snake Eyes: G.I. Joe Origins | 10/19/21 | Paramount | Action | $28.26 | 50% | 35.06 | – | 11% |
| 5 | 6 | F9: The Fast Saga | 9/21/21 | Universal | Action | $173.01 | 52% | 34.57 | – | 12% |
| 6 | 4 | Don’t Breathe 2 | 10/26/21 | Sony Pictures | Horror | $32.64 | 53% | 25.85 | – | 11% |
| 7 | 11 | Black Widow | 9/14/21 | Disney/Marvel | Action | $183.65 | 59% | 24.03 | – | 17% |
| 8 | 7 | Old | 10/19/21 | Universal | Thriller | $48.24 | 45% | 23.96 | – | 9% |
| 9 | New | Pig | 11/2/21 | Decal | Drama | $3.19 | 51% | 22.09 | – | – |
| 10 | 9 | Stillwater | 10/26/21 | Universal | Drama | $14.47 | 39% | 19.97 | – | – |
| 11 | 94 | Nobody | 6/22/21 | Universal | Action | $27.27 | 90% | 18.27 | – | 79% |
| 12 | 8 | Injustice | 10/19/21 | Warner | Animated | DTV | 67% | 17.56 | – | 13% |
| 13 | 15 | Space Jam: A New Legacy | 10/5/21 | Warner | Comedy | $70.53 | 43% | 15.65 | – | 4% |
| 14 | New | A Timeless Christmas | 11/2/21 | Cinedigm/Hallmark | Drama | TV Movie | – | 15.38 | – | – |
| 15 | 5 | Hocus Pocus | 6/4/02 | Disney | Fantasy | Re-release | 23% | 15.34 | – | 4% |
| 16 | 12 | The Protégé | 10/19/21 | Lionsgate | Action | $7.45 | 54% | 14.79 | – | 11% |
| 17 | ** | Wonder Woman 1984 | 3/30/21 | Warner | Action | $46.53 | 90% | 14.63 | 0.4% | 78% |
| 18 | 10 | The Nightmare Before Christmas | 8/26/08 | Disney | Animated | Re-release | 14% | 13.55 | – | – |
| 19 | 19 | Cruella | 9/21/21 | Disney | Comedy | $86.10 | 52% | 13.46 | – | 9% |
| 20 | New | The Crown: The Complete Fourth Season | 11/2/21 | Sony Pictures | Drama | Web | 18% | 13.05 | – | – |
| Source: NPD VideoScan First Alert (based on unit sales from reporting retailers) | ||||||||||
| MediaPlayNews.com | ||||||||||
| * Units Sold Compared to No. 1 Title | ||||||||||
| ** Re-entered the Top 100 | ||||||||||
| † Percentage of Overall Disc Sales in a 3D format; 3D is considered a Blu-ray version and is also part of the BD Share for each title. | ||||||||||
| †† Percentage of Overall Disc Sales in a UHD BD format; UHD is considered a Blu-ray version and is also part of the BD Share for each title. | ||||||||||
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